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Disulfiram

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29 أبريل - 03 مايو, 2025
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Product details

What is Disulfiram?

Disulfiram is a medication used in alcohol addiction treatment that works by inhibiting aldehyde dehydrogenase, causing unpleasant reactions if alcohol is consumed. It was the first drug approved by the FDA for alcohol dependency treatment.

Medical Uses

  • Alcohol dependence treatment
  • Alcohol deterrent therapy
  • Part of comprehensive alcohol rehabilitation programs
  • Sometimes used in cocaine dependence (off-label)
  • Chronic alcohol abuse management

Common Side Effects

  1. General Side Effects
    • Drowsiness
    • Headache
    • Metallic taste
    • Skin rash
  2. Gastrointestinal Effects
    • Nausea
    • Vomiting
    • Bad breath
  3. Neurological Effects
    • Fatigue
    • Vision changes
    • Nerve pain
  4. Psychiatric Effects
    • Confusion
    • Mood changes
    • Psychotic reactions (rare)
  5. Disulfiram-Alcohol Reaction
    • Flushing
    • Severe headache
    • Nausea and vomiting
    • Heart palpitations
    • Difficulty breathing
    • Confusion
Frequently Asked Questions
  1. Q: How long after taking Disulfiram can I drink alcohol?

A: You should wait at least 14 days after stopping Disulfiram before consuming any alcohol. The medication can remain active in your system for up to 2 weeks.

  1. Q: What products should I avoid while taking Disulfiram?

A: Avoid all products containing alcohol, including mouthwash, cough medicines, cooking wines, and some food preparations. Even small amounts can trigger a reaction.

  1. Q: How long do I need to be alcohol-free before starting Disulfiram?

A: You must be alcohol-free for at least 12 hours before taking your first dose of Disulfiram. Most practitioners recommend 24-48 hours of sobriety.

  1. Q: What happens if I drink alcohol while taking Disulfiram?

A: You will experience severe unpleasant reactions including flushing, nausea, vomiting, headache, chest pain, and palpitations. In severe cases, this reaction can be life-threatening.

  1. Q: How long will I need to take Disulfiram?

A: The duration varies by individual but typically ranges from several months to years as part of a comprehensive treatment program for alcohol dependence.

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